What if you stopped being satisfied?

How many times in your life have you heard someone say someting along the lines of “Such is life.”? How about “There’s nothing we can do about it.”, or “We just have to accept it.”? If you’re like me, the answer would be way too many times.

I’ve always loathed such sayings with a passion. I couldn’t never really understand why, until I learned about a mindset called complacency. …


A scientific review of methods used to rejuvenate organisms

In the past years (2012–2021), multiple exciting discoveries in the world of genomics have been made. From CRISPR, that allowed us to edit more efficiently, to revelations about the relationship between genome and epigenome, we are now more equipped than ever to rejuvenate organisms efficiently by modifying their genes.

Epigenome reprogramming is one particularly impactful way of achieving this. Itcan be done multiple ways. In this review, I explore the differents methods used to achieve it and their effects based on recent experiments. …


Could they do the same for humans?

In 2016, an experiment was conducted by researchers of the Salk Institute for Biological Studies. Its goal was to determine if the cyclic short-term expression of the four Yamanaka factors in-vivo would rejuvenate living breathing beings such as mice. Amazingly, it turns out it could. But how?

How did they activate the Yamanaka factors? Were there unwanted side-effects, effects we would want to avoid in humans? How long did the results last? Let’s explore the process behind the discovery that made countless sensational headlines a few years back.

But first — What Are The Yamanaka Factors?

Yamanaka factors, which are named…


Could this be the fountain of youth we’ve been looking for?

Had you been born 12 000 years ago, dying because of some hungry predator would be normal to you. Flash forward to only 150 years ago, death by tuberculosis would be your usual.

You might think you would never actually think of those horrible events as normal, no matter when you lived. But now, consider this. You were born in a time where aging is seen as normal. Like predation and pandemics, should the inevitability of aging not be questioned?

Aging is, after all, a process far from harmless. It is literally defined as “the life-long accumulation of ‘damage’ to…


Imagine you wanted to make yourself a shirt, but didn’t have any scissors or anything sharp to cut out the fabric. You’d have to tear it with your own hands, and that would make sense if you didn’t have anything better to work with. But what if you actually had scissors, but kept tearing that fabric using your hands? Would that make any sense? No, of course not! The tool is right there next to you! Why not use it?

And yet, that is exactly what’s happening with the way we interpret CT scans today. There are many problems with…


How light informs us about stars and galaxies

Because they are invisible, we tend to forget particles are the building blocks of everything. It’s crazy to think such minuscule, secretive objects are so fundamental to all aspects of today’s science. And yet here they are, teaching us about everything in our elegant universe.

Today and for the duration of this article, photons, the particles of light, will help you complete a mission you and your team of astronomy researchers have been assigned. …

Flavie Prévost

TKS innovator. I mostly write about healthspan.

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